السيرة الذاتية

Abdulrhman S. Alsayari, Ph.D
Assistant Professor of Pharmacognosy
Department of Pharmacognosy, College of Pharmacy
King Khalid University
P. O. Box 1882, Abha 61441
Kingdom of Saudi Arabia
Tel. (+96617) 241-7736     Fax. (+96617) 241-8203
 

Education

  • Ph.D. (Natural products chemistry & drug discovery): Title [Anticancer and Antiviral Activities of Cucurbitacins Isolated from Cucumis prophetarum var. Prophetarum Growing in the Southwestern Region of Saudi Arabia] South Dakota State University, USA; August 2014.
  • B. Sc (Pharmaceutical Sciences): College of Pharmacy, King Saud University, Saudi Arabia; May 2005.

 

Experience

  • Dean of College of Pharmacy, King khalid University, Saudi Arabia (September, 2015- to date).
  • Chairman of Pharmacognosy Department, College of Pharmacy, King Khalid University, Saudi Arabia (August 2015 – September 2015).
  • Assistant Professor (Pharmacognosy) Department of Pharmacognosy, College of Pharmacy, King Khalid University, Saudi Arabia (January 2015- to date).
  • Teaching Assistant, Department of Pharmacognosy, College of pharmacy, King Khalid University, Saudi Arabia (November 2005)

 

Area of Expertise

  • Natural products separation (marine and higher plants), structural elucidation, bioassay guided fractionation and structural modification.
  • Different kind of chromatography for separation and analytical techniques such as LC, HPLC (analytical and preparative), GC and gel permeation.
  • Spectroscopic analysis using IR, UV, MS, 1D-NMR (1H, 13C-NMR) and 2D-NMR (Including COSY, NOESY, HSQC and HMBC).  In addition, the ability for measurement on NMR machine.
  • Experience in cell culture techniques and bioassay.
  • Running variety of computational modeling software.

 

Scientific Meeting Attendance

  • The 9th International Pharmaceutical Sciences Conference & Exhibition “Future of Medications in the 21st Century”, College of Pharmacy, King Saud University, Saudi Arabia (December 2005).
  • 45th ACS Midwest Regional Meeting (The Energy of Chemistry) Wichita, KS, USA (Oct. 27-30, 2010)
  • 241st ACS National Meeting & Exposition (Chemistry of Natural Resources) Anaheim, California, USA (March 27-31, 2011)
  • International Congress on Natural Products Research (Global Change, Natural Products, and Human Health) New York City, New York, USA (July 28 – August 1, 2012)
  • 2nd International Conference on Medicinal Chemistry & Computer Aided Drug Designing Hampton Inn Tropicana, Las Vegas, USA (October 15-17, 2013).
  • 249th ACS National Meeting & Exposition (Chemistry of Natural Resources) Denver, Colorado, USA (March 22-26, 2015).

 

 

Publications

  • Sikander M, Hafeez BB, Malik S, Alsayari A, Halaweish FT, Yallapu MM, Chauhan SC, Jaggi M. Cucurbitacin D exhibits potent anti-cancer activity in cervical cancer. Sci Rep. 2016 Nov 8.
  • Alsayari A, Kopel L, Salama Ahmed M, Pay A, Carlson T, Halaweish FT., Design, Synthesis, and Biological Evaluation of Steroidal Analogs as estrogenic / anti-estrogenic agents. Steroids. 2016 Nov 19

 

Abstracts

  • Abdulrhman Alsayari, F. Halaweish, M. Baruah, N. Rice "study of novel estrogen and cucurbitane analogs affinity and cytotoxicity toward breast cancer cell lines." 45th ACS Midwest Regional Meeting (The Energy of Chemistry) Wichita, KS, USA (Oct. 27-30, 2010).

 

  • Abdulrhman. Alsayari, F. Halaweish, M. Baruah, " novel estrogen and cucurbitane analogs: potential drug candidate targeting breast cancer" 241st ACS National Meeting & Exposition (Chemistry of Natural Resources) Anaheim, California, USA (March 27-31, 2011).

 

  • F. Halaweish, Abdulrhman. Alsayari, Kopel L, Salama Ahmed "Design and biological screening of steroidal analogs as selective estrogen receptor modulators" 249th ACS National Meeting & Exposition (Chemistry of Natural Resources) Denver, Colorado, USA (March 22-26, 2015).

 

  • Abdulrhman. Alsayari, Kopel L, F. Halaweish "Development of novel antiestrogenic estrone analogs targeting breast cancer" 2nd International Conference on Medicinal Chemistry & Computer Aided Drug Designing Hampton Inn Tropicana, Las Vegas, USA (October 15-17, 2013).

 

  • Abdulrhman. Alsayari, M Darweesh, F Halaweish, CCL Chase, "Anti- bovine viral diarrhea virus activity of cucurbitacins as new potential antiviral agents" International Congress on Natural Products Research (Global Change, Natural Products, and Human Health) New York City, New York, USA (July 28 – August 1, 2012)

 

Professional Affiliations

  • The Saudi Pharmaceutical Society.
  • The American Society of Pharmacognosy,
  • The American Chemical Society.

Courses Taught at King Saud University, College of Pharmacy

  • PHG 415: pharmaceutical biotechnology
  • PHG 416: isolation & identification of natural products.
  • PHR 543: research project

References Available Upon Request